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SERVICES

Technology transfer

with licensing of fermentation and semi-synthesis processes producing:

• Bacteriostatic antibiotic API
• Anticancer API
• Vitamins
• Aminoacids
• Cosmetic Ingredients
• Steroids
• Statins
• Other bioproducts.

» Technology transfer - more details  The technology transfer available in Biofin Laboratories is based on a direct evaluation of the technology by the client, with test in fermenter.

Our technology transfer is not a blind procedure or a simple flask demonstration: the client technicians attend to the run of the process, with deep explication of:

» laboratory procedures

» fermentation phase

» down-stream phase.

During the technology transfer we delivers strain and book of technology.

Biofin Laboratories is available for training and lectures at the Biofin’s centre in order to make easier the implementation of the technology to the client site.

In case of client request, Biofin scientists will attend the industrial implementation of the process, assuring confidential assistance.

Biofin scientists will assist the client in the industrial implementation of the process, in case of client request, assuring confidential assistance.

Process improvements:

• Strain development programmes
• Improvement of industrial procedure
• Optimization of production cost.

» Process improvements - more details  The background of our leaders and technicians is both academic and industrial. The development or the improvement of a process in Biofin Laboratories is based on:

• Scientific literature fonts.
• Identification of optimal starting strain.
• Application of traditional strain improvement processes.
• Genetic engineering procedure.
• Laboratory modification or starting implementation of the process parameters based on the metabolic property of the strain.
• Scale up of the process, based on the industrial experience in production of our leaders, and based on the almost twenty years long experience in technology implementation in client site of our technicians.
• Strict evaluation of the feasibility of the process in industrial scale.

Engineering and Consulting:

• Feasibility studies for existing and new processes
• Preliminary basic engineering
• Basic engineering
• Industrial fermenter design
• Process scale-up from laboratory to industrial scale
• Sterile design and evaluation of existing production plants.

» Engineering and Consulting - more details  Biofin Laboratories has an industrial background, and all research and development are based on this specific experience.

Fermenter sizing and design, services sizing, recovery equipment identification and sizing, purification equipment identification and sizing, plant design and manpower evaluation can be provide by our technical staff.

Based on the market evolution, influenced by the local or world social changes and the new scientific prospective, we can provide FEASIBILITY STUDY, a technical overview on the practicability of a business dedicated to a bio-product or to a class of bio-product.

Based on our technologies (or on a client technology), due to our deep knowledge of the process engineering, we can provide BASIC ENGINEERING or PRELIMINARY BASIC ENGINEERING, necessary to define the detailed engineering of a plant.

The Biofin's knowledge of the practical problems involved in the industrial implementation of fermentation and semisynthesis technologies allows to define the best plant parameters and design, and to face the adaptation of a process to a ready plant.